Nonsyndromic Synchronous Multifocal Central Giant Cell Granulomas of the Maxillofacial Region: Report of a Case

نویسندگان

  • Anita Munde
  • Priyanka Modi
  • Ravindra Karle
  • Pranali Wankhede
  • Safia Shoeb
چکیده

Central giant cell granuloma (CGCG) is a benign proliferation of fibroblasts and multinucleated giant cells that almost exclusively occurs in the jaws. It commonly occurs in young adults showing a female predilection in the anterior mandible. Multifocal CGCGs in maxillofacial region are very rare and suggestive of systemic diseases such as hyperparathyroidism, an inherited syndrome such as Noonan-like multiple giant cell lesion syndrome or other disorders. Only 10 cases of multifocal CGCGs in the maxillofacial region without any concomitant systemic disease have been reported in the English literature. Here, we report an unusual case of 36 year-old female presented with non-syndromic synchronous, multifocal CGCGs in the left posterior mandible and left posterior maxilla without any concomitant systemic disease. Relevant literature is reviewed and the incidence, clinical features, radiological features, differential diagnosis and management of CGCGs are discussed.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Multifocal Central Giant Cell Granuloma - A Case Report

Central giant cell granuloma is a benign, aggressive neoplasm composed of multinucleated giant cells that almost exclusively occurs in the jaws though extra-gnathic incidence is rare.Multifocal CGCGs of the jaws are very rare and suggestive of systemic diseases such as hyperparathyroidism,an inherited syndrome such as Noonan-like multiple giant cell lesion syndrome or other disorders.Very few c...

متن کامل

Multiple Central Giant Cell Granuloma of the Mandible: A Case Report

Introduction: Central giant cell granuloma is a benign lesion but sometimes has aggressive proliferation composed of multinucleated giant cells in a background of spindle and ovoid mesenchymal cells. Multifocal central giant cell granuloma of jaws is very rare and usually associated with hyperparathyroidism and some syndromes. We described an un-usual case of a 22-year-old man with idi-opathic ...

متن کامل

Multiple Synchronous Central Giant Cell Granulomas of the Maxillofacial Region: A Case Report

ally present as a painless lesion and a solitary radiolucent expansion is seen on the simple radiographs. This disease is most commonly diagnosed in the third decade of life, and females are twice as likely to be affected as males (1). The gnathic cases of giant cell granuloma have accounted for 1-7% of all the benign lesions in several previously reported oral surgical series. Jaw lesions affe...

متن کامل

A 38- year demographic study of central and peripheral giant cell granulomas of the jaws

Objective: The purpose of this study was to retrospectively analyze the demographic characteristics of patients with central peripheral giant cell granulomas (CGCGs) / (PGCGs) an Iranian population. Methods: In this 38-year retrospective study, the data were obtained from records of 1019 patients with CGCG and PGCG of the jaws referred to the Department of Oral and Maxillofacial, Pathology, ...

متن کامل

A Case of Recurrent Multifocal Central Giant Cell Granulomas

One case of recurrent multifocal central giant cell granulomas (CGCG) is presented. Initially, the lesions presented concurrently in the maxilla and mandible with subsequent recurrence in the mandible. Now, two recurrences are seen in the maxillary sinus and ethmoid region. The literature regarding multifocal CGCG is reviewed.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2015